Simultaneous Estimation of Thermal Parameters of Living Tissues Using Noninvasive Method

A new noninvasive measurement method is presented for the simultaneous estimation of the key thermal parameters of the cylindrical living tissue. The numerical calculation and the theoretical analysis for the corresponding two-dimensional model are carried out. The results have proved the feasibility of the proposed method. The selection, crossover and mutation operators of a new real-coded GA are respectively designed in this paper to solve the problem of parameter optimization. Then, a set of simulations are performed to verify the effectiveness of the proposed method as well as to optimize the design of the experiments. Finally, series of experiments are performed to measure the thermal parameters of the human forearm. The experimental results indicate that the obtained parameters, such as the thermal conductivity, the blood perfusion and the volumetric heat capacity, are within the range of the reference values. The proposed method is easy to implement in practical applications.